The sites of origin brain stem neurotensin and serotonin projections to the rodent nucleus raphe magnus

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The Sites of Origin of Brain Stem Neurotensin and Serotonin Projections to the Rodent Nucleus

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Effects of Electrolytic Lesions of the Ventrolateral Periaqueductal Gray and Nucleus Raphe Magnus on Morphine – Induced Antinociception in the Nucleus Cuneiformi

A B S T R A C TIntroduction: The nucleus cuneiformis (NCF) and ventrolateral periaqueductal gray (vlPAG), two adjacent areas, mediate the central pain modulation and project to the nucleus raphe magnus (NRM). Methods: This study examined whether the antinociceptive effect of morphine microinjected into the NCF is influenced by inactivation of vlPAG and NRM in rats. Animals were bilaterally micr...

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Nitric oxide in the nucleus raphe magnus modulates cutaneous blood flow in rats during hypothermia

Objective(s): Nucleus Raphe Magnus (NRM) that is involved in the regulation of body temperature contains nitric oxide (NO) synthase. Considering the effect of NO on skin blood flow control, in this study, we assessed its thermoregulatory role within the raphe magnus. Materials and Methods: To this end, tail blood flow of male Wistar rats was measured by laser doppler following the induction of ...

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Analgesic effect of morphine microinjected into the nucleus raphe magnus after electrolytic lesion of nucleus cuneiformis in tail-flick and formalin tests in rat

Introduction: The antinociceptive effect of morphine is, in part, mediated through the activation of a descending pathway. One of the major components of this pathway is the nucleus raphe magnus (NRM). Our previous study demonstrated the involvement of NRM in the analgesic effect of morphine microinjected into the nucleus cuneiformis (NCF) in a descending manner. The aim of the current study...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1982

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.02-07-00829.1982